MP12 Antidepressant treatment pathway for adults (over 18) with moderate to severe depression

Medicine management
Issue No

Target Audience

All Clinical Staff CWP
Clinical Staff working within the Commissioning CCGs


This pathway is a whole system approach in that it has been agreed in consultation with the CCGs, bearing in mind that 95% of depression is managed within primary care. The pathway concentrates on the treatment of depression with medication for adults over 18 years (for child and adolescent management refer to the NICE clinical guidelines Sept 2005) including comparison of anti-depressants and guidance on stopping and swapping anti-depressants. This pathway should be used in conjunction with the full depression care pathway.


Lead executive
Medical Director

Authors details
Chief Pharmacist - 01244 397379

Policy dates & history

Implementation Date

09 December 2012

Review Date

09 December 2017

Approval Meeting

Medicines Management Group


MP12 Antidepressant treatement pathway for adults Issue 5.pdf

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